(Met(O)27)-Glucagon (1-29) (human, rat, porcine) ( ——— )

产品货号. M40228 CAS No. 75217-63-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) 是一种修饰的胰高血糖素。(Met(O)27)-Glucagon (1-29) (human, rat, porcine) 在大鼠肝细胞中具有与天然胰高血糖素相同的最大葡萄糖合成活性，但其活性较低，这表明蛋氨酸在胰高血糖素与其肝脏受体的结合中起关键作用。
产品描述

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor.
体外实验

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体内实验

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1. Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63.?

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